Minimal Strain Sets Explaining All Diagnostic Classes (Number of Markers Explained):
Solution 1: C57BL/6NRj
C57BL/6NRj: 28 / 40 (70.0%)
Notes
Genetic QC analysis (GQC) was performed on representative samples from the donor submission and provides a baseline reference. Regardless of the material ordered (live mice, sperm, embryos, resuscitated animals), the provided material is guaranteed to contain the primary genetic alteration of interest; however, the composition of the genetic background may vary (See Reproducibility sections of the report for details). The impact of genetic background on previously reported phenotypes has not been evaluated.
GQC analysis was done on two XY samples, EV2972 and UM3072, at the time of importation and the conclusions are consistent in all samples. The results of the analysis are congruent with the SDS and UM3072 is the representative sample selected for the report. The strain background is C57BL/6N. The mitochondrial genome and Y chromosome are consistent with the C57BL/6N background and the following constructs are detected in all samples: bpA, hCMV_a, hCMV_b.
The genome of the MMRRC:50611 strain is 100 % inbred.